Resource id #3DrugId:1d00000002resource(4) of type (mysql result) Drug Search

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Drug ID: 1d00000002

Drug Name: Abacavir Sulfate and Lamivudine

Generic Names: Epzicom |

Category: Antiretroviral Agents

Legal Status: Non Opioid Prescription only drug

OTC: No

Indication for Mother: Category C:
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Recommended Dose: abacavir sulfate 600 mg and lamivudine 300 mg

Recommended In: This combination medication contains antiretroviral agents, prescribed for HIV-1 infection. It blocks HIV reproduction. It prevents HIV reproduction in the body.

Directions For Use: It comes as a tablet abacavir sulfate 600 mg and lamivudine 300 mg to take by mouth, with or without food.

Storage: Store it at controlled room temperature (25°C).

Dosage Forms: Tablets |

Side Effects: Most Common - Hypersensitivity, sleeplessness, depression, headache, migraine, fatigue, uneasiness, dizziness, nausea, vomiting, diarrhea, rash, fever, abdominal pain, abnormal dreams, anxiety, cough or Inflammation of the pharynx, eye problems, enlarged lymph nodes and swollen ankles.

Body as a Whole - Redistribution/accumulation of body fat.

Gastrointestinal - Mouth ulcer, sore throat.

Metabolic - Blood sugar.

General - Weakness.

Blood - Anemia.

Hypersensitivity - Hives.

Musculoskeletal - Muscle weakness, CPK elevation, damaged skeletal muscle.

Central Nervous System - Tingling, nerve disease, seizures.

Respiratory - Abnormal breath sounds/wheezing.

Skin - Hair loss, redness, Stevens-Johnson syndrome.

In Case of Overdose: Abacavir

There is no known antidote for abacavir. It is not known whether abacavir can be removed by peritoneal dialysis or hemodialysis.



Lamivudine

One case of an adult ingesting 6 grams of lamivudine was reported; there were no clinical signs or symptoms noted and hematologic tests remained normal. It is not known whether lamivudine can be removed by peritoneal dialysis or hemodialysis.

Call local emergency number or take patient to nearby medical center.

Avoid If: Caution should be exercised in patients with history of liver or kidney impairment, heart disease, diabetes or cholesterol, poor immunity, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

It doesn’t stop the spread of infections to others; avoid sexual contact during the treatment period.

Drug Interaction: The drug interactions described are based on studies conducted with the individual nucleoside analogues. In humans, abacavir and lamivudine are not significantly metabolized by cytochrome P450 enzymes nor do they inhibit or induce this enzyme system; therefore, it is unlikely that clinically significant drug interactions will occur with drugs metabolized through these pathways.



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