Resource id #3DrugId:1d00000004resource(4) of type (mysql result) Drug Search

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Drug ID: 1d00000004

Drug Name: Abarelix

Generic Names: Plenaxis |

Category: Chemotherapy

Legal Status: Non Opioid Prescription only drug


Indication for Mother: Category X:
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Recommended Dose: Intra-Muscular - The recommended dose is 100 mg on day 1, 15, 29 (week 4) and every 4 weeks thereafter.

Recommended In: This medication is a gonadotropin releasing-hormone (GnRH) antagonist, prescribed for prostate cancer (to treat it partially). It reduces testosterone (hormone) level in your body, which involves in the growth of most prostate cancers.

Directions For Use: It comes as a solution for injection to be administered by a healthcare provider into the buttock.

Storage: Store the medication as directed by your physician.

Dosage Forms: Intra-Muscular Injection |

Side Effects: Genitourinary - Hot flushes, pain, breast enlargement, breast pain/nipple tenderness, painful urination, urination frequency, nausea, urinary retention and urinary tract infection.

Central Nervous System - Sleep disturbances, dizziness, syncope, headache, and fatigue.

Heart - Hypotension, peripheral edema.

Miscellaneous - Allergic reactions, back pain, constipation, swelling in the extremities, temporary redness of face and neck, upper respiratory tract infection and diarrhea.

In Case of Overdose: The maximum tolerated dose of Abarelix has not been determined. The maximum dose used in clinical studies was 150 mg. There have been no reports of accidental overdose with Abarelix.

Avoid If: Caution should be exercised in patients with history of heart disease, including long QT syndrome, abnormal heart rhythm, liver disease, who are taking other medications, any allergy, and during breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Monitor testosterone blood levels, prostate specific antigen (PSA), or liver function tests level regularly while taking this medication.

Drug Interaction: No formal drug/drug interaction studies with Abarelix were performed. Cytochrome P-450 is not known to be involved in the metabolism of Abarelix. Abarelix is highly bound to plasma proteins (96 to 99%).

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