Resource id #3DrugId:1d00000026resource(4) of type (mysql result) Drug Search

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Drug ID: 1d00000026

Drug Name: Acrivastine and Pseudoephedrine

Generic Names: Semprex D | Benadryl plus

Category: Antihistamines And Decongestants

Legal Status: Non Opioid Prescription only drug

OTC: No

Indication for Mother: Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Recommended Dose: Adults- The recommended dose is one capsule (8mg/60mg), every 4 to 6 hours four times a day.

Recommended In: This medication contains a non-sedating antihistamine (acrivastine), and a nasal decongestant(pseudoephedrine) which is prescribed to temporarily relieve seasonal allergic rhinitis such as sneezing, rhinorrhea, pruritus, lacrimation, nasal congestion. It is also used for itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold. It narrows blood vessels and shrinkage of the nasal mucous membranes by blocking histamine at H1 receptor sites.

Directions For Use: It comes as a capsule to take by mouth, with or without food. Take this with food if stomach upset occurs.

Storage: Store at 15 to 25 C in a dry place and protected from light.

Dosage Forms: Capsule

Side Effects: Central Nervous System - Drowsiness, headache, dizziness, nervousness, sleeplessness.

Gastrointestinal - Nausea, dry mouth/nose/throat, weakness, indigestion, inflammation of pharynx.

Heart - Increased heart rate, increased blood pressure.

Miscellaneous - Increased cough, difficulty in passing urine and painful menstruation.

In Case of Overdose: There have been no reports of overdosage with acrivastine and pseudoephedrine Capsules.

Avoid If: Caution should be exercised in patients with history of high blood pressure, heart disease, diabetes, overactive thyroid, increased eye pressure, kidney disease, stomach or bowel obstruction, peptic ulcer, urinary tract problems, prostate disease, difficulty in urinating, who are taking other medications, any allergy, elderly, children, during pregnancy and breastfeeding.

Should not be used in children under 12 years of age and people who have taken a monoamine-oxidase inhibitor antidepressant (MAOI) in the last 14 days.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption.

It may affect blood sugar levels; monitor blood sugar regularly.

Drug Interaction: MAO inhibitors and beta-adrenergic agonists increase the effects of sympathomimetic amines. Concomitant use of sympathomimetic amines with MAO inhibitors can result in a hypertensive crisis. Because MAO inhibitors are longacting, acrivastine and pseudoephedrine Capsules should not be taken with an MAO inhibitor or for 14 days after stopping use of an MAO inhibitor. Because of their pseudoephedrine content, acrivastine and pseudoephedrine Capsules may reduce the antihypertensive effects of drugs that interfere with sympathetic activity. Care should be taken in the administration of acrivastine and pseudoephedrine Capsules concomitantly with other sympathomimetic amines because the combined effects on the cardiovascular system may be harmful to the patient Concomitant administration of acrivastine and pseudoephedrine Capsules with alcohol and other CNS depressants may result in additional reductions in alertness and impairment of CNS performance and should be avoided.



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