Resource id #3DrugId:1d00000043resource(4) of type (mysql result) Drug Search

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Drug ID: 1d00000043

Drug Name: Alefacept

Generic Names: Amevive

Category: Immunosuppressants

Legal Status: Non Opioid Prescription only drug

OTC: No

Indication for Mother: Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Recommended Dose: The recommended dose is 15 mg given once weekly as an intramuscular injection.

Recommended In: This medication is an immunosuppressant, prescribed for moderate to severe psoriasis. It works by stopping the action of certain cells in the body that cause the symptoms of psoriasis.

Directions For Use: It comes as a solution to be administered by a healthcare provider into the large muscle.

Storage: Store it in refrigerator (2-8C).

Dosage Forms: Intra muscular Injection

Side Effects: Serious Effects - Malignancy and abnormal decrease in lymphocytes.

Most Common - Dizziness, increased cough, muscle pain, nausea, swelling at the injection site and sore throat.

Miscellaneous - Itching, chills, cough, and accidental injury.

In Case of Overdose: The highest dose tested in humans (0.75 mg/kg intravenous) was associated with chills, headache, arthralgia, and sinusitis within one day of dosing. Patients who have been inadvertently administered an excess of the recommended dose should be closely monitored for effects on total lymphocyte count and CD4+ T lymphocyte count.

Avoid If: Caution should be exercised in patients with history of cancer, recurrent infection, who are taking radiation therapy, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

It should not be used in children.
Avoid live vaccination while taking this medication.

Contraindicated in patients with HIV, and hypersensitivity.

Drug Interaction: Drug interaction studies have not been conducted with Alefacept.



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