Drug ID: 1d00000049
Drug Name: Alglucerase injection
Generic Names: Ceredase
Legal Status: Non Opioid Prescription only drug
Indication for Mother: Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Recommended Dose: Adults and children 2 years of age and older.
IV - Initial dosage may be as little as 2.5 units/kg 3 times a week upto 60 units/kg as frequently as once a week or as infrequently as every 4 week.
Recommended In: This medication is an enzyme, prescribed for type I Gaucher disease, an inherited metabolic disorder.
Directions For Use: It comes as a solution for injection to be administered by a healthcare provider into the vein.
Storage: Store it in refrigerator (2 - 8°C).
Dosage Forms: Intravenous injection
Side Effects: Local - Discomfort, itching, burning, swelling and pus.
Miscellaneous - Fever, abdominal discomfort, nausea, vomiting, fatigue, weakness, headache, swelling in the extremities and diarrhea.
In Case of Overdose: No obvious toxicity was detected after single doses up to 234 units/kg. There is no experience with larger doses.
Avoid If: Caution should be exercised in patients with history of prostate cancer, any allergy, children especially less than 10 years old, during pregnancy and breastfeeding.
Monitor liver function, kidney function, and blood counts regularly while taking this medication.
Extreme caution needed in children less than 2 years of age.
Drug Interaction: No information provided.