Drug ID: 1d00000102
Drug Name: Amyl Nitrite
Generic Names: Amyl Nitrite
Category: Skeletal Muscle Relaxants
Legal Status: Non Opioid Prescription only drug
Indication for Mother: Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Recommended Dose: Adult - Inhalation 0.3 mL as needed; 2 to 6 inhalations from 1 capsule are usually sufficient. May be repeated in 3 to 5 min.
Recommended In: This medication is a muscle relaxant, prescribed for angina pectoris. It works by dilating blood vessels.
Directions For Use: It comes as a capsule for inhalation; inhale by mouth as directed by your physician.
Storage: Store it in a cold place (2°-8°C).
Dosage Forms: Inhalation Capsule
Side Effects: Common - Headache, dizziness and flushing.
Miscellaneous - Fainting, feeling of excitement, involuntary passing of urine and feces, relaxation of involuntary muscles, low blood pressure, pallor, cold sweat, fast heart rate, shortness of breath, restlessness, weakness, vomiting and nausea.
In Case of Overdose: Inhaled doses of 5 to 10 drops of amyl nitrite (amyl nitrite inhalant) may cause violent flushing of the face, accompanied by a feeling of imminent bursting of the head and very excessive heart action. The inhalation of larger amounts may produce a feeling of suffocation and muscular weakness. Symptoms comparable to shock may be produced (such as weakness, restlessness, sweating, pallor, nausea, vomiting, syncope and incontinence) attributable to pooling of blood in the post arteriolar vessels and failure of the venous blood to return to the heart.
Measures which facilitate venous return such as head-low posture, deep breathing and movement of extremities may be used. The use of epinephrine aggravates the shocklike reaction. Methylene blue should be injected for treatment of severe methemoglobinemia with dyspnea. For treating cyanide poisoning, methylene blue is contraindicated where nitrites cause iatrogenic methemoglobinemia.
Avoid If: Caution should be exercised in patients with history of chest pain, drug abuse, methemoglobin reductase deficiency, any allergy, who are taking other medications, children, and breastfeeding women.
It may cause dizziness, light-headedness, or fainting while standing or drinking alcohol. Avoid alcohol consumption while taking this medication.
Do not drive a car or operate machinery while taking this medication.
Amyl nitrite is very flammable.
This medication comes in a glass capsule covered by a protective cloth. The cloth covering allows you to crush the glass capsule between your fingers without cutting yourself.
Contraindicated in patients with cerebral hemorrhage (stroke), increased eye pressure, recent head injury, during pregnancy.
Drug Interaction: Taking amyl nitrite (amyl nitrite inhalant) after drinking alcohol may worsen side effects and may cause severe hypotension and cardiovascular collapse.