Resource id #3DrugId:1d00000149resource(4) of type (mysql result) Drug Search

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Drug ID: 1d00000149

Drug Name: Azithromycin

Generic Names: Azi OD 500 | Azitive (250mg) | Acin (500mg) | Aziprime (500mg) | Azifix (30ml) | Throcure DS (500mg) | Azibest (250mg) | Azilid (250mg) | Azitus 100 (15ml) | Swithro 200 (15ml) | Azinova (250mg) | Zifro (500mg) | Azee (250mg) | Swithro 100 (15ml) | 3A (500mg) | Rozil (250mg) | Zitis (250mg) | Tyzit (500mg) | Kelaz (500mg) | Azis (250mg) (Ecocare) | Azisafe DT (100mg) | Itha (500mg) | Azison DT (250mg) | Edzy (250mg) | Shie | Azimaid DT (100mg) | Azito (15ml) | Azalid-Kit | Vicon (15ml) | Azinic (250mg) | Zithromax | More

Category: Antibiotics

Legal Status: Non Opioid Prescription only drug

OTC: No

Indication for Mother: Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Recommended Dose: Adult: Respiratory tract, Skin and soft tissue infections- 500 mg once daily for 3 days. Or 500mg on day 1 followed by 250mg on days 2 to 5.

Typhoid- 500 mg once daily for 7 days.
Uncomplicated gonorrhoea- 2 g single dose.

Granuloma inguinale- Initial: 1 g, then 500 mg/day until all lesions has healed completely.

Chancroid/Chlamydial urethritis: 1 g single dose Prophylaxis of disseminated MAC infections 1.2 g once weekly.

Treatment or secondary prophylaxis: administered along with other antimycobacterials: 500 mg once daily.

Recommended In: This medication is a macrolide antibiotic used for various bacterial infections such as infections of the middle ear, throat, bronchus, sinuses, skin and soft tissue. It is also useful in treating pneumonia, typhoid, gonorrhoea, granuloma inguinale and chancroid. It prevents bacterial growth.

Directions For Use: It comes as a tablet and liquid to take by mouth, with or without food.

Storage: Intravenous: Store below 30C. Store it in room temperature and in an airtight container. Keep away from children and pets.

Dosage Forms: Tablet | Solution

Side Effects: Heart- Chest pain, abnormal heart rate, low blood pressure, abnormal heart rhythm with QT prolongation and torsades de pointes.

Gastrointestinal- Indigestion, loss of appetite, flatulence, gastritis, loose stools, vomiting, colitis and constipation.

Genitourinary- Kidney failure and vaginal inflammation.

Blood- Decrease in platelets.

Liver- Abnormal liver function, jaundice and liver failure.

Central Nervous System- Weakness, tingling, fatigue, uneasiness, dizziness/vertigo, headache, drowsiness, hyperactivity, nervousness, agitation and syncope.

Skin- Itching, severe allergic reactions, irritation, fungal infection, sweating, hives and blistering.

ENT- Hearing loss and/or tinnitus, abnormalities in taste and smell sensation.

Hypersensitivity - Allergic reaction.

Respiratory- Increased cough, inflammation of pharynx, pleural effusion and rhinitis.

In Case of Overdose: In the event of overdosage, general symptomatic and supportive measures are indicated as required.

Avoid If: Caution should be exercised in patients with history of cystic fibrosis, human immunodeficiency virus (HIV), irregular heartbeat, or kidney or liver disease, during pregnancy and breastfeeding.

Drug Interaction: Nelfinavir

Co-administration of nelfinavir at steady-state with a single oral dose of azithromycin resulted in increased azithromycin serum concentrations. Although a dose adjustment of azithromycin is not recommended when administered in combination with nelfinavir, close monitoring for known adverse reactions of azithromycin, such as liver enzyme abnormalities and hearing impairment, is warranted.

Warfarin

Spontaneous post-marketing reports suggest that concomitant administration of azithromycin may potentiate the effects of oral anticoagulants such as warfarin, although the prothrombin time was not affected in the dedicated drug interaction study with azithromycin and warfarin. Prothrombin times should be carefully monitored while patients are receiving azithromycin and oral anticoagulants concomitantly.

Potential Drug-Drug Interaction With Macrolides

Interactions with the following drugs listed below have not been reported in clinical trials with azithromycin; however, no specific drug interaction studies have been performed to evaluate potential drug-drug interaction. However, drug interactions have been observed with other macrolide products. Until further data are developed regarding drug interactions when digoxin or phenytoin are used with azithromycin careful monitoring of patients is advised.



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