Resource id #3DrugId:2d00000026resource(4) of type (mysql result) Drug Search

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Drug ID: 2d00000026

Drug Name: Benzphetamine

Generic Names: Didrex

Category: Anorectal Preparations

Legal Status: Non Opioid Prescription only drug

OTC: No

Indication for Mother: Category X
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Recommended Dose: The recommended dose range is 25 to 50 mg one to three times daily.

Recommended In: This medication is an anorectic agent, prescribed for obesity. It works by suppressing appetite.

Directions For Use: It comes as tablet to take by mouth, with or without food.

Storage: Store it at controlled room temperature (20 to 25 C).

Dosage Forms: Tablet

Side Effects: Heart - Palpitations, fast heart rate and elevation of blood pressure.

Central Nervous System - Over-stimulation, restlessness, dizziness, sleeplessness, tremor, sweating, headache and depression.

Gastrointestinal - Dryness of the mouth, unpleasant taste, nausea, diarrhea and other gastrointestinal disturbances.

Allergic - Hives, rash and itching.

Genitourinary - Changes in sexual activity.

In Case of Overdose: Acute overdosage with amphetamines may result in restlessness, tremor, tachypnea, confusion, assaultiveness and panic states. Fatigue and depression usually follow the central stimulation. Cardiovascular effects include arrhythmias, hypertension or hypotension, and circulatory collapse. Gastrointestinal symptoms include nausea, vomiting, diarrhea, and abdominal cramps. Hyperpyrexia and rhabdomyolysis have been reported and can lead to a number of associated complications. Fatal poisoning is usually preceded by convulsions and coma.

Management of acute amphetamine intoxication is largely symptomatic and includes sedation with a barbiturate. If hypertension is marked, the use of a nitrite or rapidly acting alpha receptor blocking agent should be considered. Experience with hemodialysis or peritoneal dialysis is inadequate to permit recommendations in this regard.

Acidification of the urine increases amphetamine excretion.

Avoid If: Caution should be exercised in patients with history of heart disease, lung or breathing problems, high blood pressure, sugar, over active thyroid, mental illness, any allergy, who are taking other medications, during pregnancy and breastfeeding.

It may cause drowsiness or dizziness, do not drive a car or operate machinery while taking this medication.

Avoid abrupt withdrawal.

It should not be used in children less than 12 years.

It may affect blood sugar level; monitor sugar level regularly while taking this medication.

Contraindicated in patients with increased eye pressure, uncontrolled high blood pressure, heart diseases, overactive thyroid, who are taking or within 14days of use of monoamine oxidase inhibitors, central nervous stimulants, during pregnancy and hypersensitivity.

Drug Interaction: Hypertensive crises have resulted when sympathomimetic amines have been used concomitantly or within 14 days following use of monoamine oxidase inhibitors. benzphetamine should not be used concomitantly with other CNS stimulants.

Amphetamines may decrease the hypotensive effect of antihypertensives. Amphetamines may enhance the effects of tricyclic antidepressants.

Urinary alkalinizing agents increase blood levels and decrease excretion of amphetamines. Urinary acidifying agents decrease blood levels and increase excretion of amphetamines.



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