Resource id #3DrugId:3d00000005resource(4) of type (mysql result) Drug Search

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Drug ID: 3d00000005

Drug Name: Caffeine

Generic Names: Ofcold | Setcold | Sinkoryl Plus | Binilon | Crocin Pain Relief | Coldrif | Novacet -D | Cafepar | Tolagin Plus | Sudamine | Folate | Khasinil | Cozy Plus | Trimol | Corinite | Coryna | Corinite | Ibufen | Wincold Tab | Norflam Plus | Migril | Histran | Fevril | Sudrex | Coldargic Tab | Febrimol - C | Vuscof -DP | Coldy | Zocold P | Atcold | Cafcit | More

Category: CNS Stimulant

Legal Status: Non Opioid Prescription only drug


Indication for Mother: Category B
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Recommended Dose: It may be administered orally at a dose of 100-200 mg , repeated after 3-4 hours as needed. For apnea in premature babies, it is administered intravenously or orally at an initial dose of 20 mg/kg, followed by 5 mg/kg/day.

Recommended In: This medication stimulates the brain; hence it is used as a central nervous stimulant. It is used along with analgesics and/or ergotamine for migraine (severe headaches with nausea). It is also used for a breathing condition (apnea) in premature infants.

Directions For Use: It comes as a tablet, capsule to take by mouth. It is also available in injection, administered by the healthcare providers, directly into the vein.

Storage: Store it 25C. Store it in air tight container and keep away from children.

Dosage Forms: Tablet | Capsule | Intravenous Injection

Side Effects: Central Nervous System- Confusion, dizziness, sleeplessness, restlessness, excitement, nervousness, tinnitus, light depression and fatigue, visual disturbance, muscular tremor, headache, lightheadedness, seizures.

Heart- Fast heart rate, abnormal heart rhythm.

Gastrointestinal- Vomiting, nausea, diarrhea, necrotizing enterocolitis, gastritis.

Skin- Rash, dry skin.

Genitourinary- Increased urination.

Metabolic- Low sugar.

Respiratory- Difficulty in breathing.

Miscellaneous- Hypersensitivity (eg, dermatitis, rhinitis, bronchial asthma), feeding intolerance, sepsis, accidental injury, stroke.

In premature infants, caffeine in addition may cause the following side effects- Skin breakdown, damage to the retina of the eye, bleeding from gastrointestinal tract, kidney failure, increased clotting of blood, acidosis, accumulation of water in the lungs and bleeding in the brain.

In Case of Overdose: Signs and symptoms reported in the literature after caffeine overdose in preterm infants include fever, tachypnea, jitteriness, insomnia, fine tremor of the extremities, hypertonia, opisthotonos, tonic-clonic movements, nonpurposeful jaw and lip movements, vomiting, hyperglycemia, elevated blood urea nitrogen, and elevated total leukocyte concentration. Seizures have also been reported in cases of overdose. One case of caffeine overdose complicated by development of intraventricular hemorrhage and long-term neurological sequelae has been reported.

Treatment of caffeine overdose is primarily symptomatic and supportive. Caffeine levels have been shown to decrease after exchange transfusions. Convulsions may be treated with intravenous administration of diazepam or a barbiturate such as pentobarbital sodium.

Avoid If: Do not change the dose without consulting with your doctor.

While taking this medication avoid drinking excess amount of caffeine- containing drinks.

Though caffeine may increase alertness, it can cause dizziness. Hence avoid doing anything that requires concentration and can cause disability or death in case of an accident, e.g. driving a car or operating machinery.

It is not to be used as a substitute for sleep.

Caution should be exercised in patients with history of heart disease, kidney disease, liver disease, stomach problems (peptic ulcer), seizures, during pregnancy and breast feeding.

Do not administer solutions containing sodium benzoate to children.

Drug Interaction: Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products your infant may use, especially of: adenosine, cimetidine, dipyridamole, fluvoxamine, lithium, theophylline, vemurafenib.

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