Resource id #3DrugId:3d00000016resource(4) of type (mysql result) Drug Search

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Drug ID: 3d00000016

Drug Name: Canakinumab

Generic Names: Ilaris

Category: Monoclonal antibodies

Legal Status: Non Opioid Prescription only drug

OTC: No

Indication for Mother: Category C
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Recommended Dose: Adult- The recommended dose is 150 mg for patients with body weight greater than 40 kg.

Child- The recommended dose is 15 to 40 kg with an inadequate response; the dose can be increased to 3 mg/kg.

Recommended In: This medication is an interleukin-1 beta-blocker, prescribed for auto-inflammatory diseases known as cryopyrin-associated periodic syndrome (CAPS). It decreases interleukin-1 beta's activity.

Directions For Use: It comes as a powder for injection (diluted with fluid) to be administered by a healthcare provider under the skin.

Storage: Store it in refrigerator (2 to 8C). Do not freeze it.

Dosage Forms: Subcutaneous Injection

Side Effects: Most Common - Diarrhea, influenza, headache and nausea.

Miscellaneous - Increased weight, musculoskeletal pain, fainting, stomach inflammation, nose inflammation, decrease in white blood cells.

In Case of Overdose: In the case of overdose, it is recommended that the subject be monitored for any signs and symptoms of adverse reactions or effects, and appropriate symptomatic treatment be instituted immediately.

Avoid If: Caution should be exercised in patients with history of autoimmune disorder, cancer, hepatitis B or C, tuberculosis, infection, flu-like symptoms, any allergy, who are taking other medications, during pregnancy and breast-feeding.

It may cause dizziness, do not drive a car or operate machinery while taking this medication.

Avoid contact with people who have infections.

It should not be used in children less than 4 years old.

Contraindicated in patients with severe infection, HIV/AIDS, hepatitis B or C, who are taking tumor necrosis factor (TNF) blocker, and known hypersensitivity.

Drug Interaction: Some products that may interact with this drug include: other IL-1 blockers (such as anakinra, rilonacept), live vaccines, TNF-blockers (such as adalimumab, etanercept, infliximab).



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