Resource id #3DrugId:3d00000019resource(4) of type (mysql result) Drug Search

Main    A    B    C    D    E    F    G    H    I    J    K    L    M    N    O    P    Q    R    S    T    U    V    W    X    Y    Z    Main   

Drug ID: 3d00000019

Drug Name: Capecitabine

Generic Names: Capscare (500mg) | Capehope | Distamine (500mg) | Xeloda | Capres (150 mg) | Capres | Naprocap | Capegard | Capiibine (500 mg) | Xabine | Distamine (150mg) | Xabine | Captabin | Capiibine | Capxcel | Xelocel | Xeloda

Category: Chemotherapy

Legal Status: Non Opioid Prescription only drug


Indication for Mother: Category D
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Recommended Dose: The recommended dose is 1250 mg/m2 administered orally twice daily (morning and evening; equivalent to 2500 mg/m2 total daily dose) for 2 weeks followed by 1-week rest period given as 3-week cycles.

Recommended In: This medication is an antimetabolite, prescribed for breast cancer and colorectal cancer. It prevents the growth of cancer cells.

Directions For Use: It comes as a tablet to take by mouth, with food, two times per day.

Storage: Store it at room temperature 25 C.

Dosage Forms: Tablet

Side Effects: Gastrointestinal Disorders - Diarrhea, nausea, mouth ulcer, vomiting, abdominal pain, gastrointestinal hemorrhage constipation, upper abdominal pain and indigestion.

Skin - Hand-and-Foot Syndrome, hair loss, rash and redness.

General - Injection site pain, irritation, swelling, fatigue, fever, chest pain, back pain, weakness and lethargy.

Central Nervous System - Dizziness, depression, sleep disorders, headache and abnormal taste.

Metabolic - Loss of appetite.

Eye - Eye inflammation and loss of vision.

Blood - Decreased white blood cells.

Respiratory - Nosebleed, cough and sore throat.

In Case of Overdose: The manifestations of acute overdose would include nausea, vomiting, diarrhea, gastrointestinal irritation and bleeding, and bone marrow depression. Medical management of overdose should include customary supportive medical interventions aimed at correcting the presenting clinical manifestations.

Avoid If: Caution should be exercised in patients with history of heart, liver or kidney disease, any allergy, bone marrow problems, pain, redness, swelling, tingling, tenderness of the palms and soles, who are taking other medications, elderly, children, during pregnancy and lactation.

Avoid vaccination while taking this medication.

It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.

It may reduce platelet counts; avoid bruising or injury.

Monitor blood counts and blood electrolytes while taking this medication.

Contraindicated in patients with kidney problems or dihydropyrimidine dehydrogenase (DPD) enzyme deficiency and hypersensitivity.

Drug Interaction: Before using this medication, tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use, especially: folic acid (including multivitamins with folic acid), leucovorin, metronidazole, tinidazole.

This drug can change the removal of other drugs from your body by affecting certain liver enzymes. These affected drugs include: "blood thinners" (e.g., warfarin), fosphenytoin, phenytoin.

If you are currently using any of these medications listed above, tell your doctor or pharmacist before starting capecitabine.

Capecitabine is very similar to fluorouracil. Do not use medications containing fluorouracil while using capecitabine.

Main    A    B    C    D    E    F    G    H    I    J    K    L    M    N    O    P    Q    R    S    T    U    V    W    X    Y    Z    Main