Drug ID: 3d00000024
Drug Name: Captopril
Generic Names: Capotril (25 mg) | Capotril (12.5 mg) | Aceten (25mg) | Angiopril | Acezide | Aceten (12.5 mg) | Capotril | Capotril H | Angiopril -DU | Captopril | Capoten
Category: ACE Inhibitors
Legal Status: Non Opioid Prescription only drug
Indication for Mother: Category D :
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Recommended Dose: The recommended dose is 25-150 mg two or three times daily. The maximum dose is 450 mg daily.
Recommended In: This medication is an angiotensin-converting enzyme inhibitor (ACE inhibitor), prescribed for high blood pressure (hypertension), congestive heart failure, myocardial infarction and kidney problems caused by diabetes. It decreases certain chemicals actions that tighten the blood vessels.
Directions For Use: It comes as a tablet to take by mouth, on an empty stomach, 1 hour before or 2 hours after a meal.
Storage: Store it at room temperature 15 o to 30° C.
Dosage Forms: Tablet
Side Effects: Heart - Fast heart rate, chest pain, palpitations, heart attack, congestive heart failure, stroke, low blood pressure and fainting.
Body as a whole - Allergic reactions.
General - Weakness and breast enlargement in males.
Skin - Rash, itching, redness, skin disorders and scaling.
Gastrointestinal - Inflammation of pancreas/tongue and difficulty in swallowing.
Blood - Anemia.
Liver - Jaundice and liver inflammation.
Metabolic - Electrolyte disturbances.
Musculoskeletal - Muscle pain and weakness.
Central Nervous System - In coordination, confusion, depression, nervousness and drowsiness.
Respiratory - Asthma, nose inflammation and lung disorder.
Eye - Blurred vision.
Genitourinary - Impotence.
In Case of Overdose: Correction of hypotension would be of primary concern. Volume expansion with an intravenous infusion of normal saline is the treatment of choice for restoration of blood pressure.
While captopril may be removed from the adult circulation by hemodialysis, there is inadequate data concerning the effectiveness of hemodialysis for removing it from the circulation of neonates or children.
Avoid If: Caution should be exercised in patients with history of swelling of the lips, eyes or tongue, poor blood circulation, hardening of skin, sugar, heart disease, autoimmune disease, any allergy, who are taking other medications, children, during pregnancy and breast feeding.
It may cause dizziness or lightheadedness, do not drive a car or operate machinery and get up slowly from bed while taking this medication.
Monitor blood pressure, blood potassium or other electrolyte levels and urine tests regularly while taking this medication.
It may not work as well in black patients.
Contraindicated in patients with diabetes and known hypersensitivity.
Drug Interaction: Some products that may interact with this drug include: aliskiren, lithium, drugs that may increase the level of potassium in the blood (such as ARBs including losartan/valsartan, birth control pills containing drospirenone).
Check the labels on all your medicines (such as cough-and-cold products, diet aids, or NSAIDs such as ibuprofen, naproxen) because they may contain ingredients that could increase your blood pressure or worsen your heart failure. Ask your pharmacist for more details.
A very serious reaction may occur if you are getting injections for bee/wasp sting allergy (desensitization) and are also taking captopril. Make sure all your doctors know which medicines you are using.
This product may interfere with certain laboratory tests (including acetone urine test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.