Drug ID: 3d00000035
Drug Name: Carboprost
Generic Names: Coboprost 125 | Prostospan (1ml) | Deviprost | Prostodin (1 ml) | Caboprost | Prostodin | Prostospan (0.5ml) | Hemabate
Category: Endocrine and Metabolic Agents
Legal Status: Non Opioid Prescription only drug
Indication for Mother: Category C :
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Recommended Dose: Adult: Pregnancy termination in the 2nd trimester 250 mcg, repeat at 1.5-3.5-hrly depending on response. Max: 12 mg.
Postpartum hemorrhage 250 mcg at 15-90 min intervals.
Recommended In: This medication is a synthetic prostaglandin analogue, prescribed for termination of pregnancy and also used for postpartum hemorrhage. It induces uterine muscle contractions and can trigger abortion in early pregnancy.
Directions For Use: It comes as a solution for injection to be administered by a healthcare provider.
Storage: Refrigerate at 2-8°C.
Dosage Forms: Injection
Side Effects: Most Common- Nausea, vomiting, diarrhea and excessive uterine bleeding.
Less Common- Abdominal pain, flushing, shivering, headache, dizziness, hypotension, fever/chills, difficulty in breathing and lung swelling.
In Case of Overdose: If overdose is suspected, contact a poison control center or emergency room immediately.
Avoid If: Caution should be exercised in patients with history of heart /lung disorders, increased eye pressure, asthma, epilepsy, severe liver or kidney dysfunction, high/low blood pressure, diabetes, during pregnancy and lactation.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Take full course of treatment.
Contraindicated in patients with pelvic inflammatory disease, heart, lung, liver or kidney disease, hypersensitivity.
Drug Interaction: Consult your pharmacist.