Drug ID: 3d00000039
Drug Name: Carmustine
Generic Names: BiCNU
Legal Status: Non Opioid Prescription only drug
Indication for Mother: Category D :
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
Recommended Dose: The recommended dose as a single agent in previously untreated patients is 150 to 200 mg/m² intravenously every 6 weeks. This may be given as a single dose or divided into daily injections such as 75 to 100 mg/m² on 2 successive days.
Recommended In: This medication is an anti-cancer drug, prescribed for certain types of cancers like multiple myeloma, brain tumor, Hodgkin’s and non – Hodgkin’s lymphoma. The medication restricts the advancement of the cancer cell growth in the body.
Directions For Use: It comes as a solution for injection, administered by healthcare providers.
Storage: Store in refrigerator at 2-8°C; away from light.
Dosage Forms: Injection
Side Effects: Body as whole- Fever, chills, sore throat, loss of appetite or weight and swelling in ankle and feet region.
Skin - Pale skin, easy bruising and redness.
Blood- Abnormal bleeding.
Heart - Rapid heart beat.
Respiratory - Wheezing and chest pain.
Gastrointestinal- Nausea, vomiting and diarrhea.
Central Nervous System- Confusion, headache, weakness, dizziness, drowsiness and mood changes.
Eye - Vision imbalance.
Delayed effect- Liver and kidney damage, lung fibrosis and stomach upset.
Potentially Fatal- Delayed and cumulative bone marrow depression.
In Case of Overdose: No proven antidotes have been established for carmustine overdosage. If overdose is suspected, contact a poison control center or emergency room immediately.
Avoid If: Avoid immunization while taking this medication.
If you are taking any other medication, inform the doctor.
Caution should be exercised in patients with history of liver or kidney impairment, decrease in blood count, bone marrow depression, lung disease, during pregnancy and breast-feeding.
Monitor blood count, liver, kidney and lung function regularly while taking this medication.
It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
Avoid alcohol consumption while taking this medication.
Drug Interaction: Some products that may interact with this drug include: digoxin, drugs that may decrease bone marrow function (e.g., azathioprine, cimetidine), nalidixic acid, phenytoin.