Drug ID: 3d00000046
Drug Name: Cefazolin
Generic Names: Cefadin (500 mg) | Lyzolin | Cefadin | Orizolin | Cezolin (500 mg) | Sefazol (1 gm) | Cezolin | Azolin | Cefadin | Cefadin | Sefazol | Ciprid (1 gm) | Orizolin | Azolin | Reflin (500 mg) | Reflin (1 gm) | Ciprid | Ozolin (500mg) | Orizolin | Cefadin | Lyzolin (1 gm) | Azolin | Reflin | Cezolin (1 gm) | Reflin | Ozolin (1gm) | Reflin | Cefadin (250 mg) | Cefadin (1 gm) | Prezolin (1000 mg) | Ancef | Kefzol | More
Legal Status: Non Opioid Prescription only drug
Indication for Mother: Category B :
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Recommended Dose: Susceptible infections 0.5-1 g 6-12 hourly. Max: 6 g/day, up to 12 g/day in severe infections.
Surgical prophylaxis- 1 g 30-60 minutes pre-op, followed by 0.5-1 g during surgery for lengthy procedures. Continue with 0.5-1 g 6-8 hourly post-op for 24 hour.
Recommended In: This medication is a cephalosporin antibiotic, mainly used to treat bacterial infections in different parts of the body (the lung, bone, joint, stomach, blood, heart valve, and urinary tract). It is also used to prevent bacterial infections before, during, or after certain surgeries. It works by killing sensitive bacteria.
Directions For Use: It comes as a solution for injection, to be administered by a healthcare provider. It is usually administrated by either intramuscular injection (injection into a large muscle) or intravenous infusion (injection into a vein).
Storage: Store at 25°C.Store in refrigerator. Do not freeze the medication.
Dosage Forms: Intramuscular Injection | Intravenous Infusion
Side Effects: Central Nervous System- Hyperactivity.
Gastrointestinal- Abdominal pain, anal itching, loss of appetite, inflammation of colon, diarrhea, nausea, fungal infection of mouth, stomach cramps, vomiting.
Genitourinary- Genital itching (including genital fungal infection, vaginal inflammation, vulvar itching).
Liver- Liver inflammation.
Blood- Anemia, bleeding, decrease in white blood cells, platelets.
Lab tests- Increased level of liver enzymes, prolonged blood clotting time.
Local- Pain, inflammation of veins.
Musculoskeletal- Tightness of muscle.
Genitourinary- Increased BUN (Blood, urea, Nitrogen) and creatinine, kidney function impairment, toxic nephropathy.
Miscellaneous- Allergy (including anaphylaxis, drug fever, eosinophilia, severe allergic reactions, toxic hives), super infection.
In Case of Overdose: If overdose is suspected, contact a poison control center or emergency room immediately.
Avoid If: Caution should be exercised in patients with history of liver, kidney, and gastrointestinal diseases.
It may harmful to kidney function, pregnancy and breast feeding.
Consider possibility of pseudo membranous colitis in patients who present with diarrhoea after antimicrobial usage.
Risk of seizures in patients on high doses, especially in kidney failed patients.
It may decrease prothrombin activity; monitor prothrombin time in patients at risk e.g. those on anticoagulant treatment, prolonged antimicrobial treatment or those with kidney or liver impairment.
Avoid long-term use, otherwise it will cause secondary infection.
Drug Interaction: Some products that may interact with this drug include: aminoglycoside antibiotics (e.g., tobramycin, gentamicin), "blood thinners" (e.g., warfarin), chloramphenicol, probenecid, live bacterial vaccines.
Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.
This medication may interfere with certain laboratory tests (including Coombs' test), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.