Drug ID: 3d00000049
Drug Name: Cefepime
Generic Names: Pineriv | Pimeriv | Kampi 250 | Ivipime | Sefdin (1g) | Kefage | Maxicef (500 mg) | Inj Sefdin | Magnova 500 | Potentox 2.5 | Kefage (2 gm) | Supime | Efepime | Kampi | Micropime (500mg) | Natapime (250mg) | Cefudix | Supime (1000mg) | Ultipime (1 gm) | Ivipime (1gm) | Maxicef (1 gm) | Cepime | Forpar | Patriat | Novapime (2 gm) | Biopime (1 gm) | Cefudix (1 gm) | Orpime | Potentox | Zipime (1 gm) | Maxipime | More
Legal Status: Non Opioid Prescription only drug
Indication for Mother: Category B :
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Recommended Dose: UTI- The recommended dose is 0.5-1 g 12 hourly for 7-10 days.
Empirical therapy for febrile neutropenia- 2 g 8 hourly for 7 days or until resolution of neutropenia.
Recommended In: This medication is cephalosporin antibiotic, prescribed for certain bacterial infections. It kills sensitive bacteria.
Directions For Use: It comes as a solution for injection, administered by a healthcare provider either into a large muscle or vein over 30 minutes.
Storage: Injection: In dry state: Store at 2-25°C and protected from light. After reconstitution: This solution is stable for 24 hour at controlled room temperature (2-25°C) and for 7 days under refrigeration (2-8°C).
Dosage Forms: Reconstituted vial for Intramuscular injection
Side Effects: Central Nervous System- Headache.
Gastrointestinal- Nausea, vomiting, diarrhea, inflammation of colon, including pseudomembranous colitis, oral candidiasis.
Skin- Rash, itching, hives.
Miscellaneous- Hypersensitivity, including, allergic reaction, toxic epidermal blistering, rash, inflammation or veins, pain or inflammation at injection site; fever.
In Case of Overdose: Patients who receive an overdose should be carefully observed and given supportive treatment. In the presence of renal insufficiency, hemodialysis, not peritoneal dialysis, is recommended to aid in the removal of cefepime from the body. Accidental overdosing has occurred when large doses were given to patients with impaired renal function. Symptoms of overdose include encephalopathy (disturbance of consciousness including confusion, hallucinations, stupor, and coma), myoclonus, seizures, and neuromuscular excitability.
Avoid If: Caution should be exercised in patients with history of penicillin or cephalosporin allergy, gastro intestinal disease, especially colitis; lactation, pregnancy, seizures.
It may decrease prothrombin activity; monitor prothrombin time in patients with poor nutritional state, kidney or liver impairment and those on prolonged treatment.
Prolonged treatment may result in overgrowth of non-susceptible organisms, resulting in superinfection.
Consider the possibility of Clostridium difficile associated diarrhea in patients who present with diarrhea after treatment.
Patient may develop with increased risk of neurotoxicity.
In diabetes patients - it may cause the results of some tests for urine glucose to be wrong. Becareful while changing the dose of your diabetes medicine.
Hypersensitivity to cephalosporins.
Drug Interaction: Some products that may interact with this drug include: aminoglycoside antibiotics (e.g., tobramycin, gentamicin), chloramphenicol, probenecid, live bacterial vaccines.
Although most antibiotics probably do not affect hormonal birth control such as pills, patch, or ring, some antibiotics may decrease their effectiveness. This could cause pregnancy. Examples include rifamycins such as rifampin or rifabutin. Be sure to ask your doctor or pharmacist if you should use additional reliable birth control methods while using this antibiotic.
This medication may interfere with certain medical/laboratory tests (e.g., urine glucose tests), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.